Hormone Replacement Therapy (HRT) is again in the news, once again with possible causal association for developing breast cancer. Statistical analysis performed by M.D.Anderson's team revealed strong association (but no cause-to-effect relationship) between declining breast cancer cases and parallel decline in use of HRT in post-menopausal women since mid-2002. The decline occurred primarily in women age 50-69, the researchers find, and was predominantly seen in estrogen-receptor(ER)-positive cancer. Ravdin and Berry strongly stress, however, that their study is not suggesting that all women stop their use of HRT. "This study is not saying that an individual woman will reduce her absolute risk of developing breast cancer by 15 percent by immediately discontinuing use of HRT," Berry says.
Read brief report at EurekAlert! 18 Apr 2007
Original article: Ravdin PM et al. | The Decrease in Breast-Cancer Incidence in 2003 in the United States | N Engl J Med 2007(Apr 19);356:1670-1674
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Thursday, April 19, 2007
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